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John A Kellum, MD, FCCM, FACP (Work Group Co-Chair), is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine at the University of Pittsburgh. In addition, he is the Director of the Program on Bioengineering and Organ Support for the CRISMA (Clinical Research Investigation and Systems Modeling of Acute Illness) Center at the University of Pittsburgh. Dr Kellum is actively involved in education, research, and administration. His research interests span various aspects of critical-care medicine, but center in critical-care nephrology, sepsis, multiorgan failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 300 publications and served as editor and contributor to recent texts including Continuous Renal Replacement Therapy, Critical Care Nephrology, and Management of Acute Kidney Problems. Dr Kellum has won several awards for teaching and has given more than 400 seminars and invited lectures worldwide related to his research. Advisor/Consultant: Abbott; Alere; Astute Medical; Baxter; CytoSorbents; EBI; Eli Lilly; Fresenius; Gambro; Siemens; Spectral Diagnostics Speaker: Baxter; Fresenius; Gambro Grant/Research Support: Astute Medical; Baxter; CytoSorbents; Gambro